These Regulations amend the Misuse of Drugs Regulations 2001 (the “2001 Regulations”). Regulation 3 adds groups of ‘NBOMe’ compounds and groups of benzofuran compounds to Schedule 1 to the 2001 Regulations. Regulation 4 adds Lisdexamphetamine to Schedule 2 and regulation 5 adds Tramadol to Schedule 3. Regulation 6 adds Zaleplon and Zopiclone to Schedule 4. The schedule in which a controlled drug is placed primarily affects the extent to which the drug can be lawfully imported, exported, produced, supplied or possessed and dictates the record keeping, labelling and destruction requirements in relation to that drug. Regulation 7 amends The Misuse of Drugs (Safe Custody) Regulations 1973 to insert Tramadol into the list of exempted drugs in Schedule 1 to those Regulations.