These Regulations amend the Branded Health Service Medicines (Costs) Regulations 2018 (S.I. 2018/345) (the “Statutory Scheme Regulations”). The amendments update the payment percentages and introduce a new approach for calculating the amount of the net sales income manufacturers and suppliers subject to the Statutory Scheme Regulations will pay to the Secretary of State based on whether the supplies of the presentations are of newer presentations or older presentations.