Cancel the clinical trial into puberty blockers & safeguard vulnerable children
The government is aware of the potential irreversible impact (physical and emotional) of puberty blockers, having acknowledged an 'unacceptable safety risk’ following the Cass Review. Yet, hundreds of children are about to be given puberty blockers under a government-sanctioned trial.
Signatures
147,699
signatures
Government response threshold (10,000) · 10,000/10,000 · reached
Debate threshold (100,000) · 100,000/100,000 · reached
- 23 MAR 2026Debate was scheduled — outcome pending
- 02 FEB 2026Government respondedDepartment of Health and Social CareGovernment reply
We are following the expert advice of the Cass Review to establish a clinical trial to determine the relative benefits and harms of puberty suppression in young people with gender incongruence.
Read full response - 12 JAN 2026100,000 signatures reachedEligible to be considered for debate
- 09 JAN 202610,000 signatures reachedEligible for a government response
- 08 JAN 2026Petition opened for signaturesCreated by James Esses
Background
We want this trial to be cancelled. We believe that the answer for children feeling dis-ease in their bodies (many of whom are autistic) is the passage of time and natural progression of puberty, coupled with explorative therapy. We believe that the answer is never medicalisation that can harm brain development, bone growth, sexual functioning, and lead to infertility, and that to put children on a path towards such harm is the antithesis of safeguarding.
Let us not be written into history as the country that knowingly harmed vulnerable children.