Addition of quadruple test to Edwards' syndrome screening pathway

The UK NSC consulted on a rapid review of modelled data conducted by NHS England. This data suggested that the quadruple screening test, which is offered to pregnant women who miss the first trimester combined screening test, should be used to screen for Edwards’ syndrome in addition to Down’s syndrome.

We therefore asked stakeholders and the public read the consultation document below to provide feedback on the following question:

Does the evidence from this rapid review demonstrate that the quadruple test is accurate enough to be added to the antenatal screening pathway for Edwards’ syndrome (Trisomy 18)?